I really don't seen an offensive or two-way shot worth pursuing here...
I recommend Saaaa-aaaa--fety
This looks like the easiest safety to pull off in getting behind the 8 ball.
Here is another option, but this seems more difficult and could leave an easy jump shot for your opponent.
You could also tie up the 8 ball with your 9 ball since you have more left on the table...this would also leave your opponent only a tough shot in the side pocket for his 2 ball.
What would you suggest to do here?